A controlled and prospective study of the anmia in the hemorrhoid was performed to 111 patients of the hemorrhoid treated at the department of surgery, Seoul National University Hospital from January to July, 1983.
The results were as follows:
1) The incidence of iron deficiency anemia was 33.3% from criteria adequate to the value of hemoglobin and one of serum iron, total iron binding capacity and transferrin saturation. Especially for the female patient at the age of 20 to 40, the incidence was 37.5% which was above the mean and the result was due to the physiologic loss in this age group.
2) The mean hematologic finding in the hemorrhoidal anemia generally showed mild iron. deficiency anemia and its value was as follows: Hemoglobin 10.9±1.8 gm%, hema tocrit 33.8±1.8, serum iron 58±12 g%, total iron binding capacity 416±32 pg%, transferrin saturation 15.5±3.1%.
3) The severity of hemorrhage was proportional to the incidence of anemia and the sign of anemia almost showed non-specific one, e.g. general weakness, lethargy etc.
4) The incidence and degree of anemia was proportional to the hemorrhoid degree and the number of piles.
5) According to the comparative study with normal and anemic population with identical hemoglobin value, the serum iron was maintained at lower level while available iron supply to the erythrocyte was not much affected.
6) The classification of the hematologic finding in the hemorrhoid was made into the grade A, B, C and its sub-grade 1,2 in relation to the amount and duration of hemorrhage. The chronic and recent scanty hemorrhage occupied the most, 70.2%.
In relation to the iron deficiency classification of Wintrobe, the grade A was late, B was early and C was latnt iron deficiency.
|